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Inhibition of Herpesvirus Replication and Herpesvirus-Induced Deoxyribonucleic Acid Polymerase by Phosphonoformate

Phosphonoformate was found to be an inhibitor of the deoxyribonucleic acid polymerase induced by the herpesvirus of turkeys. The apparent inhibition constants were 1 to 3 μM. Phosphonoformate was also able to block the replication in cell culture of Marek's disease herpesvirus, the herpesvirus of tu...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Reno, John M., Lee, Lucy F., Boezi, John A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1978
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352212/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/206200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.2.188
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