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Inhibition of Herpesvirus Replication and Herpesvirus-Induced Deoxyribonucleic Acid Polymerase by Phosphonoformate

Phosphonoformate was found to be an inhibitor of the deoxyribonucleic acid polymerase induced by the herpesvirus of turkeys. The apparent inhibition constants were 1 to 3 μM. Phosphonoformate was also able to block the replication in cell culture of Marek's disease herpesvirus, the herpesvirus...

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Bibliographic Details
Main Authors: Reno, John M., Lee, Lucy F., Boezi, John A.
Format: Artigo
Language:Inglês
Published: 1978
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC352212/
https://ncbi.nlm.nih.gov/pubmed/206200
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