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(64)Cu-ATSM pharmacokinetics in FaDu xenograft tumors and correlation with microscopic markers of hypoxia

PURPOSE: The behavior of (64)Cu-ATSM in hypoxic tumors was examined through a combination of in vivo dynamic PET imaging, and ex vivo autoradiographic and histological evaluation using a xenograft model of H&N squamous cell carcinoma. METHODS AND MATERIALS: (64)Cu-ATSM was administered during dy...

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Detalhes bibliográficos
Main Authors: McCall, Keisha C., Humm, John L., Bartlett, Rachel, Reese, Megan, Carlin, Sean
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522091/
https://ncbi.nlm.nih.gov/pubmed/22727887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2012.05.005
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