Mechanistic Studies of Polyene Enhancement of Interferon Production by Polyriboinosinic-Polyribocytidylic Acid

The production of interferon by polyriboinosinic-polyribocytidylic acid [poly(I) · poly(C)] and poly(I) · poly(C)-diethylaminoethyl-dextran in L929 cells was enhanced from 10 to 100 times by polyene macrolides, including amphotericin B (AmB), AmB methyl ester, nystatin, and filipin. AmB and its wate...

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Bibliographic Details
Main Authors: Borden, Ernest C., Booth, Bruce W., Leonhardt, Peggy H.
Format: Artigo
Language:Inglês
Published: 1978
Subjects:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC352206/
https://ncbi.nlm.nih.gov/pubmed/206199
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