Reversible Inhibition of Cellular Metabolism by Ribavirin

The broad spectrum antiviral drug ribavirin (Virazole, 1-β-d-ribofuranosyl-1,2,4-triazole-3-carboxamide) inhibits cellular macromolecular synthesis as well as cell division in eucaryotic cells. The concentration and time dependence have been studied. One-hour treatment with 25 μM ribavirin or 18 h w...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Larsson, Alf, Stenberg, Kjell, Öberg, Bo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1978
Soggetti:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352205/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/646339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.2.154
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