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Epigenetics of the Depressed Brain: Role of Histone Acetylation and Methylation

Major depressive disorder is a chronic, remitting syndrome involving widely distributed circuits in the brain. Stable alterations in gene expression that contribute to structural and functional changes in multiple brain regions are implicated in the heterogeneity and pathogenesis of the illness. Epi...

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Detalhes bibliográficos
Main Authors: Sun, HaoSheng, Kennedy, Pamela J, Nestler, Eric J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521990/
https://ncbi.nlm.nih.gov/pubmed/22692567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.73
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