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Morphologic and Gene Expression Criteria for Identifying Human Induced Pluripotent Stem Cells

Induced pluripotent stem (iPS) cells can be generated from somatic cells by the forced expression of four factors, Oct3/4, Sox2, Klf4, and c-Myc. While a great variety of colonies grow during induction, only a few of them develop into iPS cells. Researchers currently use visual observation to identi...

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Detalhes bibliográficos
Main Authors: Wakao, Shohei, Kitada, Masaaki, Kuroda, Yasumasa, Ogura, Fumitaka, Murakami, Toru, Niwa, Akira, Dezawa, Mari
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521736/
https://ncbi.nlm.nih.gov/pubmed/23272044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048677
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