The Nuclear Chaperone Nucleophosmin Escorts an Epstein-Barr Virus Nuclear Antigen to Establish Transcriptional Cascades for Latent Infection in Human B Cells

Epstein-Barr Virus (EBV) is an oncogenic γ-herpesvirus that capably establishes both latent and lytic modes of infection in host cells and causes malignant diseases in humans. Nuclear antigen 2 (EBNA2)-mediated transcription of both cellular and viral genes is essential for the establishment and mai...

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Autors principals: Liu, Cheng-Der, Chen, Ya-Lin, Min, Yi-Li, Zhao, Bo, Cheng, Chi-Ping, Kang, Myung-Soo, Chiu, Shu-Jun, Kieff, Elliott, Peng, Chih-Wen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521654/
https://ncbi.nlm.nih.gov/pubmed/23271972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003084
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