Nonfunction of the ECT2 gene may cause renal tubulointerstitial injury leading to focal segmental glomerulosclerosis

BACKGROUND: Secondary focal segmental glomerulosclerosis (FSGS) follows congenital or acquired tubulointerstitial alterations such as in Dent’s disease, Lowe syndrome, and reflux nephropathy. Failure of adequate regeneration after tubulointerstitial injury, or abnormal tubulogenesis, can disturb int...

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Hlavní autoři: Izu, Akane, Sugimoto, Keisuke, Fujita, Shinsuke, Nishi, Hitomi, Takemura, Yutaka, Okada, Mitsuru, Takemura, Tsukasa
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Japan 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521645/
https://ncbi.nlm.nih.gov/pubmed/22552385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10157-012-0636-0
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