Effects of Small-Particle Aerosols of Rimantadine and Ribavirin on Arterial Blood pH and Gas Tensions and Lung Water Content of A2 Influenza-Infected Mice
The respiratory pathophysiology of A2 influenza infection was studied in mice treated with small-particle aerosols (SPA) of rimantadine or ribavirin. Untreated infections in mice resulted in survival rates of 15% or less and were characterized by (i) severe hypoventilation (decreased P(O(2)) and inc...
Enregistré dans:
| Publié dans: | Antimicrob Agents Chemother |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1977
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/18987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.1.40 |
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