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Distribution of Amikacin in Serum, Muscle, and Fat in Children After a Single Intramuscular Injection

Amikacin concentrations in serum, muscle, and fat were determined in 41 children after intramuscular administration of 7.5 mg/kg of body weight. At 1.5 h amikacin reached peak concentrations in serum (mean value, 14.9 μg/ml) as well as in muscle (2.2 μg/g) and fat (1.89 μg/g) tissue; from then on al...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Daschner, F., Reiss, E., Engert, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1977
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/879756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.11.6.1081
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