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A computational tool for the design of live attenuated virus vaccine based on microRNA-mediated gene silencing
BACKGROUND: The microRNA-based gene-silencing machinery has been recognized as a promising approach to control viral replication and used for improving safety for the live attenuated virus vaccines. The effective host microRNA response elements (MREs) have been incorporated into a virus sequence mai...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3521223/ https://ncbi.nlm.nih.gov/pubmed/23281624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S7-S15 |
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