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A novel unbiased measure for motif co-occurrence predicts combinatorial regulation of transcription

BACKGROUND: Multiple transcription factors (TFs) are involved in the generation of gene expression patterns, such as tissue-specific gene expression and pleiotropic immune responses. However, how combinations of TFs orchestrate diverse gene expression patterns is poorly understood. Here we propose a...

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Hlavní autoři: Vandenbon, Alexis, Kumagai, Yutaro, Akira, Shizuo, Standley, Daron M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521209/
https://ncbi.nlm.nih.gov/pubmed/23282148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S7-S11
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