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Natural selection drives rapid evolution of mouse embryonic heart enhancers

BACKGROUND: Mouse E11.5 embryonic heart enhancers were found to exhibit exceptionally weak sequence conservation during vertebrate evolution compared to enhancers of other developing organs. However, it is unknown whether this phenomenon is due to elevated mutation rates, or is a consequence of natu...

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Autori principali: Liao, Ben-Yang, Weng, Meng-Pin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521173/
https://ncbi.nlm.nih.gov/pubmed/23281795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-S2-S1
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