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C5aR-dependent cell activation by physiological concentrations of C5a(desArg): Insights from a novel label-free cellular assay()

The complement anaphylatoxins C3a, C5a, and C5a(desArg) play critical roles in the induction of inflammation and the modulation of innate and acquired immune responses after binding to their G protein-coupled receptors, C3aR and C5aR. The role of C5a(desArg) in inducing cell activation has been ofte...

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Bibliografische gegevens
Hoofdauteurs: Reis, Edimara S., Chen, Hui, Sfyroera, Georgia, Monk, Peter N., Köhl, Jörg, Ricklin, Daniel, Lambris, John D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521166/
https://ncbi.nlm.nih.gov/pubmed/23041570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200834
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