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Evolved Diversification of a Modular Natural Product Pathway: Apratoxins F and G, Two Cytotoxic Cyclic Depsipeptides from a Palmyra Collection of Lyngbya bouillonii

A collection of Lyngbya bouillonii from Palmyra Atoll in the Central Pacific, a site several thousand kilometers distant from all previous collections of this chemically prolific species of cyanobacterium, was found to contain two new cancer cell cytotoxins of the apratoxin family. The structures of...

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Main Authors: Tidgewell, Kevin, Engene, Niclas, Byrum, Tara, Media, Joseph, Doi, Takayuki, Valeriote, Fred A., Gerwick, William H.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521036/
https://ncbi.nlm.nih.gov/pubmed/20512792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201000070
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