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Effect of Probenecid on the Blood Levels and Urinary Excretion of Cefamandole

Two oral 0.5-g doses of probenecid given 7 and 1 h before a single 1-g intramuscular dose of cefamandole resulted in higher serum levels of cefamandole than when cefamandole was given alone: 37 versus 20 μg per ml of serum, respectively. Cefamandole was not measurable (<0.3 μg/ml) at 8 h when it was...

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Publicado en:Antimicrob Agents Chemother
Principais autores: Griffith, R. S., Black, H. R., Brier, G. L., Wolny, J. D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1977
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352079/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/879735/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.11.5.809
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