A novel, lactase-based selection and strain improvement strategy for recombinant protein expression in Kluyveromyces lactis

BACKGROUND: The Crabtree-negative yeast species Kluyveromyces lactis has been established as an attractive microbial expression system for recombinant proteins at industrial scale. Its LAC genes allow for utilization of the inexpensive sugar lactose as a sole source of carbon and energy. Lactose eff...

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Bibliografski detalji
Glavni autori: Krijger, Jorrit-Jan, Baumann, Jan, Wagner, Melanie, Schulze, Katja, Reinsch, Christian, Klose, Thomas, Onuma, Osita F, Simon, Claudia, Behrens, Sven-Erik, Breunig, Karin D
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520740/
https://ncbi.nlm.nih.gov/pubmed/22905717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-112
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