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Leptin regulates cyclin D1 in luminal epithelial cells of mouse MMTV-Wnt-1 mammary tumors

PURPOSE: Leptin, an adipose secreted cytokine, is implicated in mammary cancer stem cell self-renewal and tumor growth in Murine Mammary Tumor Virus (MMTV)-Wnt-1 transgenic mice. In vitro studies indicate that leptin induces expression of Cyclin D1, a cell-cycle control protein necessary for mammary...

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Detaylı Bibliyografya
Asıl Yazarlar: Zheng, Qiao, Hursting, Stephen D., Reizes, Ofer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520612/
https://ncbi.nlm.nih.gov/pubmed/22692856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-012-1252-9
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