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FTY720 Markedly Increases Alloengraftment But Does Not Eliminate Host Anti-Donor T Cells That Cause Graft Rejection Upon Its Withdrawal
The immunomodulator FTY720 (FTY) is beneficial in models of graft-versus-host disease, solid organ transplantation, and autoimmunity and has been approved for use in multiple sclerosis patients. FTY modifies the homing and migration of many cell types. We now show that FTY has profound positive and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3520609/ https://ncbi.nlm.nih.gov/pubmed/22728248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2012.06.007 |
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