Inhibition of Initiation, Elongation, and Termination of Eukaryotic Protein Synthesis by Trichothecene Fungal Toxins

The 12,13-epoxytrichothecenes, specific inhibitors of protein synthesis in eukaryotes, can be subdivided further in terms of their mode of action. In addition to the I-type (initiation inhibitors) and E-types (elongation inhibitors), we found that some E-types apparently exhibit inhibition of chain...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Cundliffe, Eric, Davies, Julian E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1977
Fag:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352012/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/856003/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.11.3.491
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