Development of a Dehalogenase-Based Protein Fusion Tag Capable of Rapid, Selective and Covalent Attachment to Customizable Ligands

Our fundamental understanding of proteins and their biological significance has been enhanced by genetic fusion tags, as they provide a convenient method for introducing unique properties to proteins so that they can be examinedin isolation. Commonly used tags satisfy many of the requirements for ap...

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Main Authors: Encell, Lance P, Friedman Ohana, Rachel, Zimmerman, Kris, Otto, Paul, Vidugiris, Gediminas, Wood, Monika G, Los, Georgyi V, McDougall, Mark G, Zimprich, Chad, Karassina, Natasha, Learish, Randall D, Hurst, Robin, Hartnett, James, Wheeler, Sarah, Stecha, Pete, English, Jami, Zhao, Kate, Mendez, Jacqui, Benink, Hélène A, Murphy, Nancy, Daniels, Danette L, Slater, Michael R, Urh, Marjeta, Darzins, Aldis, Klaubert, Dieter H, Bulleit, Robert F, Wood, Keith V
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Open 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520037/
https://ncbi.nlm.nih.gov/pubmed/23248739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875397301206010055
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