Circulating Branched-chain Amino Acid Concentrations Are Associated with Obesity and Future Insulin Resistance in Children and Adolescents

BACKGROUND: Branched-chain amino acid (BCAA) concentrations are elevated in response to overnutrition, and can affect both insulin sensitivity and secretion. Alterations in their metabolism may therefore play a role in the early pathogenesis of type 2 diabetes in overweight children. OBJECTIVE: To d...

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Main Authors: McCormack, Shana E., Shaham, Oded, McCarthy, Meaghan A., Deik, Amy A., Wang, Thomas J., Gerszten, Robert E., Clish, Clary B., Mootha, Vamsi K., Grinspoon, Steven K., Fleischman, Amy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519972/
https://ncbi.nlm.nih.gov/pubmed/22961720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2047-6310.2012.00087.x
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