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Melanoma cell invasiveness is promoted at least in part by the Epidermal Growth Factor-like repeats of Tenascin-C

Tenascin-C (TNC), overexpressed in invasive growths, has been implicated in progression of melanoma but the source and function of this molecule are not well defined. We found TNC expression at the front of invading melanoma cells, and that adding TNC to matrices enhances individual melanoma cell mi...

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Autors principals: Grahovac, Jelena, Becker, Dorothea, Wells, Alan
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519964/
https://ncbi.nlm.nih.gov/pubmed/22951722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.263
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