Analysis of HIV Using a High Resolution Melting (HRM) Diversity Assay: Automation of HRM Data Analysis Enhances the Utility of the Assay for Analysis of HIV Incidence

BACKGROUND: HIV diversity may be a useful biomarker for discriminating between recent and non-recent HIV infection. The high resolution melting (HRM) diversity assay was developed to quantify HIV diversity in viral populations without sequencing. In this assay, HIV diversity is expressed as a single...

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Bibliographic Details
Main Authors: Cousins, Matthew M., Swan, David, Magaret, Craig A., Hoover, Donald R., Eshleman, Susan H.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519891/
https://ncbi.nlm.nih.gov/pubmed/23240016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051359
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