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IL-6 Is Not Necessary for the Regulation of Adipose Tissue Mitochondrial Content
BACKGROUND: Adipose tissue mitochondria have been implicated as key mediators of systemic metabolism. We have shown that IL-6 activates AMPK, a mediator of mitochondrial biogenesis, in adipose tissue; however, IL-6(−/−) mice fed a high fat diet have been reported to develop insulin resistance. These...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3519867/ https://ncbi.nlm.nih.gov/pubmed/23240005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051233 |
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