MBL-Mediated Opsonophagocytosis of Candida albicans by Human Neutrophils Is Coupled with Intracellular Dectin-1-Triggered ROS Production

Mannan-binding lectin (MBL), a lectin homologous to C1q, greatly facilitates C3/C4-mediated opsonophagocytosis of Candida albicans (C. albicans) by human neutrophils, and has the capacity to bind to CR1 (CD35) expressed on circulating neutrophils. The intracellular pool of neutrophil Dectin-1 plays...

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Autors principals: Li, Dongsheng, Dong, Bilin, Tong, Zhongsheng, Wang, Qinning, Liu, Weihuang, Wang, Yan, Liu, Wei, Chen, Jinbo, Xu, Li, Chen, Liuqing, Duan, Yiqun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519760/
https://ncbi.nlm.nih.gov/pubmed/23239982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050589
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