Učitavanje...

Expression of Mutant Huntingtin in Leptin Receptor-Expressing Neurons Does Not Control the Metabolic and Psychiatric Phenotype of the BACHD Mouse

Metabolic and psychiatric disturbances occur early on in the clinical manifestation of Huntington’s disease (HD), a neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin (HTT) gene. Hypothalamus has emerged as an important site of pathology and alterations in this area and it...

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Bibliografski detalji
Glavni autori: Lundh, Sofia Hult, Soylu, Rana, Petersén, Åsa
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519539/
https://ncbi.nlm.nih.gov/pubmed/23251447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051168
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