Timosaponin-BII inhibits the up-regulation of BACE1 induced by Ferric Chloride in rat retina

BACKGROUND: Our previous studies indicated that oxidative stress up-regulated the expression of β-amyloid precursor protein cleavage enzyme-1 (BACE1) in rat retina. Pharmacological reports have shown Timosaponin-BII, a purified extract originating from Chinese medical herb Rhizoma Anemarrhenae, is c...

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Detalhes bibliográficos
Main Authors: Huang, Ju-Fang, Shang, Lei, Liu, Pei, Zhang, Meng-Qi, Chen, Shuang, Chen, Dan, Fan, Chun-Ling, Wang, Hui, Xiong, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519506/
https://ncbi.nlm.nih.gov/pubmed/23082924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-12-189
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