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Glucocorticoids Affect 24 h Clock Genes Expression in Human Adipose Tissue Explant Cultures

AIMS: to examine firstly whether CLOCK exhibits a circadian expression in human visceral (V) and subcutaneous (S) adipose tissue (AT) in vitro as compared with BMAL1 and PER2, and secondly to investigate the possible effect of the glucocorticoid analogue dexamethasone (DEX) on positive and negative...

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Detalhes bibliográficos
Main Authors: Gómez-Abellán, Purificación, Díez-Noguera, Antoni, Madrid, Juan A., Luján, Juan A., Ordovás, José M., Garaulet, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519463/
https://ncbi.nlm.nih.gov/pubmed/23251369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050435
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