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The locus coeruleus-norepinephrine network optimizes coupling of cerebral blood volume with oxygen demand

Given the brain's uniquely high cell density and tissue oxygen levels bordering on hypoxia, the ability to rapidly and precisely match blood flow to constantly changing patterns in neural activity is an essential feature of cerebrovascular regulation. Locus coeruleus-norepinephrine (LC-NE) proj...

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Autori principali: Bekar, Lane K, Wei, Helen S, Nedergaard, Maiken
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519408/
https://ncbi.nlm.nih.gov/pubmed/22872230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.115
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