Inflammatory Mediators Alter the Astrocyte Transcriptome and Calcium Signaling Elicited by Multiple G-Protein-Coupled Receptors

Inflammation features in CNS disorders such as stroke, trauma, neurodegeneration, infection, and autoimmunity in which astrocytes play critical roles. To elucidate how inflammatory mediators alter astrocyte functions, we examined effects of transforming growth factor-β1 (TGF-β1), lipopolysaccharide...

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Main Authors: Hamby, Mary E., Coppola, Giovanni, Ao, Yan, Geschwind, Daniel H., Khakh, Baljit S., Sofroniew, Michael V.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2012
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518872/
https://ncbi.nlm.nih.gov/pubmed/23077035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1256-12.2012
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