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B(12) cofactors directly stabilize an mRNA regulatory switch

Structures of riboswitch receptor domains bound to their effector have revealed how mRNAs recognize diverse small molecules, but mechanistic details into its linkage with regulation of gene expression remain elusive(1,2). To address this, we solved crystal structures of two different classes of coba...

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Detalhes bibliográficos
Main Authors: Johnson, James E., Reyes, Francis E., Polaski, Jacob T., Batey, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518761/
https://ncbi.nlm.nih.gov/pubmed/23064232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11607
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