CCR2-dependent Recruitment of Macrophages by Tumor Educated Mesenchymal Stromal Cells Promotes Tumor Development and is Mimicked by TNF-alpha

Mesenchymal stromal cells (MSCs) tend to infiltrate into tumors and form a major component of the tumor microenvironment. These tumor-resident MSCs are known to affect tumor growth, but the mechanisms are largely unknown. We found that MSCs isolated from spontaneous lymphomas in mouse (L-MSCs) strik...

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Hoofdauteurs: Ren, Guangwen, Zhao, Xin, Wang, Ying, Zhang, Xin, Chen, Xiaodong, Xu, Chunliang, Yuan, Zeng-rong, Roberts, Arthur I., Zhang, Liying, Zheng, Betty, Wen, Ting, Han, Yanyan, Rabson, Arnold B., Tischfield, Jay A., Shao, Changshun, Shi, Yufang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518598/
https://ncbi.nlm.nih.gov/pubmed/23168163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.08.013
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