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Microtubules Enable the Planar Cell Polarity of Airway Cilia

BACKGROUND: Airway cilia must be physically oriented along the longitudinal tissue axis for concerted, directional motility that is essential for proper mucociliary clearance. RESULTS: We show that Planar Cell Polarity (PCP) signaling specifies directionality and orients respiratory cilia. Within al...

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Detalles Bibliográficos
Main Authors: Vladar, Eszter K., Bayly, Roy D., Sangoram, Ashvin, Scott, Matthew P., Axelrod, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518597/
https://ncbi.nlm.nih.gov/pubmed/23122850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.09.046
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