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Immunotargeting of tumor subpopulations in melanoma patients: A paradigm shift in therapy approaches

Several melanoma cell subpopulations with tumor-initiating and/or tumor-maintaining properties exist that may contribute to chemoresistance and tumor recurrence after standard therapies. One of these subpopulations expresses a B-cell marker, CD20. In a small pilot trial, we showed that a subset of S...

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Bibliographic Details
Main Authors: Maurer, Margarita, Somasundaram, Rajasekharan, Herlyn, Meenhard, Wagner, Stephan N.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518536/
https://ncbi.nlm.nih.gov/pubmed/23243627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21357
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