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Intratumoral alterations of dendritic-cell differentiation and CD8(+) T-cell anergy are immune escape mechanisms of clear cell renal cell carcinoma

Cytotoxic lymphocytes and dendritic cells infiltrating human renal cell carcinoma (RCC) are not sufficient to prevent tumor progression. Our studies identified alterations of the immune cell infiltrate as well as some of the underlying mechanisms. This knowledge should facilitate the development of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Noessner, Elfriede, Brech, Dorothee, Mendler, Anna N., Masouris, Ilias, Schlenker, Ramona, Prinz, Petra U.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518535/
https://ncbi.nlm.nih.gov/pubmed/23243626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21356
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