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A new dynamic model of three cell interactions for CTL responses

The exact mechanisms of CD4 help in the generation of memory cytotoxic T lymphocytes (CTLs) remain largely illusive. We propose that dendritic cells (DCs) first interact with CD4(+) T cells, resulting in DC licensing and CD4(+) T-cell priming. Thereafter, CD8(+) T cells can receive stimulatory signa...

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Bibliografiske detaljer
Main Authors: Ahmed, Khawaja Ashfaque, Wang, Lu, Xiang, Jim
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518527/
https://ncbi.nlm.nih.gov/pubmed/23243618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21175
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