An efficient T-cell epitope discovery strategy using in silico prediction and the iTopia assay platform

Functional T-cell epitope discovery is a key process for the development of novel immunotherapies, particularly for cancer immunology. In silico epitope prediction is a common strategy to try to achieve this objective. However, this approach suffers from a significant rate of false-negative results...

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Bibliographic Details
Main Authors: Fridman, Arthur, Finnefrock, Adam C., Peruzzi, Daniela, Pak, Irene, La Monica, Nicola, Bagchi, Ansuman, Casimiro, Danilo R., Ciliberto, Gennaro, Aurisicchio, Luigi
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518498/
https://ncbi.nlm.nih.gov/pubmed/23243589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21355
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