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RNA-Mediated Epigenetic Programming of Genome Rearrangements

RNA, normally thought of as a conduit in gene expression, has a novel mode of action in ciliated protozoa. Maternal RNA templates provide both an organizing guide for DNA rearrangements and a template that can transport somatic mutations to the next generation. This opportunity for RNA-mediated geno...

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Main Authors: Nowacki, Mariusz, Shetty, Keerthi, Landweber, Laura F.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518427/
https://ncbi.nlm.nih.gov/pubmed/21801022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genom-082410-101420
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