Munc13 controls the location and efficiency of dense-core vesicle release in neurons

Neuronal dense-core vesicles (DCVs) contain diverse cargo crucial for brain development and function, but the mechanisms that control their release are largely unknown. We quantified activity-dependent DCV release in hippocampal neurons at single vesicle resolution. DCVs fused preferentially at syna...

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Detalhes bibliográficos
Main Authors: van de Bospoort, Rhea, Farina, Margherita, Schmitz, Sabine K., de Jong, Arthur, de Wit, Heidi, Verhage, Matthijs, Toonen, Ruud F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518216/
https://ncbi.nlm.nih.gov/pubmed/23229896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201208024
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