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Melanocortin antagonism ameliorates muscle wasting and inflammation in chronic kidney disease
Aberrant melanocortin signaling has been implicated in the pathogenesis of wasting in chronic kidney disease (CKD). Previously, we demonstrated that agouti-related peptide (AgRP), a melenocortin-4 receptor antagonist, reduced CKD-associated cachexia in CKD mice. Our previous studies with AgRP utiliz...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518185/ https://ncbi.nlm.nih.gov/pubmed/22914778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00341.2012 |
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