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The PEG-Fluorochrome Shielding Approach for Targeted Probe Design

We provide a new approach for fluorescent probe design termed “PEG-fluorochrome Shielding,” where PEGylation enhances quantum yields while blocking troublesome interactions between fluorochromes and biomolecules. To demonstrate PEG-fluorochrome shielding, fluorochrome-bearing peptide probes were syn...

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Bibliographic Details
Main Authors: Guo, Yanyan, Yuan, Hushan, Rice, William L., Kumar, Anand T. N., Goergen, Craig J., Jokivarsi, Kimmo, Josephson, Lee
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518033/
https://ncbi.nlm.nih.gov/pubmed/23137147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja309085b
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