Toxicity of Nicotine by Repeated Intratracheal Instillation to F344 Rats

In vivo, nicotine in cigarette smoke induces various effects not only on the respiratory system but also the central and peripheral nerve systems, circulatory organs and digestive organs, and there is a possibility of promotion of lung tumorigenesis. The present experiment was conducted to examine h...

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Bibliographic Details
Main Authors: Yokohira, Masanao, Nakano, Yuko, Hashimoto, Nozomi, Yamakawa, Keiko, Ninomiya, Fumiko, Kishi, Sosuke, Saoo, Kousuke, Imaida, Katsumi
Format: Artigo
Language:Inglês
Published: Japanese Society of Toxicologic Pathology 2012
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517921/
https://ncbi.nlm.nih.gov/pubmed/23345928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.25.257
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