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Primary cilia act as mechanosensors during bone healing around an implant

The primary cilium is an organelle that senses cues in a cell’s local environment. Some of these cues constitute molecular signals; here, we investigate the extent to which primary cilia can also sense mechanical stimuli. We used a conditional approach to delete Kif3a in pre-osteoblasts and then emp...

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Bibliographische Detailangaben
Hauptverfasser: Leucht, P., Monica, S.D., Temiyasathit, S., Lenton, K., Manu, A., Longaker, M.T., Jacobs, C.R., Spilker, R.L., Guo, H., Brunski, J.B., Helms, J.A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517784/
https://ncbi.nlm.nih.gov/pubmed/22784673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.medengphy.2012.06.005
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