Protein markers of cancer-associated fibroblasts and tumor-initiating cells reveal subpopulations in freshly isolated ovarian cancer ascites

BACKGROUND: In ovarian cancer, massive intraperitoneal dissemination is due to exfoliated tumor cells in ascites. Tumor-initiating cells (TICs or cancer stem cells) and cells showing epithelial-mesenchymal-transition (EMT) are particularly implicated. Spontaneous spherical cell aggregates are someti...

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Autors principals: Wintzell, My, Hjerpe, Elisabet, Åvall Lundqvist, Elisabeth, Shoshan, Maria
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517779/
https://ncbi.nlm.nih.gov/pubmed/22901285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-359
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