Monoamine oxidase A and A/B knockout mice display autistic-like features

Converging lines of evidence show that a sizable subset of autism-spectrum disorders (ASDs) is characterized by increased blood levels of serotonin (5-hydroxytryptamine, 5-HT), yet the mechanistic link between these two phenomena remains unclear. The enzymatic degradation of brain 5-HT is mainly med...

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Autores principales: Bortolato, Marco, Godar, Sean C., Alzghoul, Loai, Zhang, Junlin, Darling, Ryan D., Simpson, Kimberly L., Bini, Valentina, Chen, Kevin, Wellman, Cara L., Lin, Rick C. S., Shih, Jean C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517692/
https://ncbi.nlm.nih.gov/pubmed/22850464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145712000715
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