TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema

Toll-like receptors (TLRs) exert important nonimmune functions in lung homeostasis. TLR4 deficiency promotes pulmonary emphysema. We examined the role of TLR4 in regulating cigarette smoke (CS)-induced autophagy, apoptosis, and emphysema. Lung tissue was obtained from chronic obstructive lung diseas...

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Detalhes bibliográficos
Main Authors: An, Chang Hyeok, Wang, Xiao Mei, Lam, Hilaire C., Ifedigbo, Emeka, Washko, George R., Ryter, Stefan W., Choi, Augustine M. K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517684/
https://ncbi.nlm.nih.gov/pubmed/22983353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00102.2012
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