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LPS-induced chorioamnionitis and antenatal corticosteroids modulate Shh signaling in the ovine fetal lung

Chorioamnionitis and antenatal corticosteroids mature the fetal lung functionally but disrupt late-gestation lung development. Because Sonic Hedgehog (Shh) signaling is a major pathway directing lung development, we hypothesized that chorioamnionitis and antenatal corticosteroids modulated Shh signa...

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Autors principals: Collins, Jennifer J. P., Kuypers, Elke, Nitsos, Ilias, Jane Pillow, J., Polglase, Graeme R., Kemp, Matthew W., Newnham, John P., Cleutjens, Jack P., Frints, Suzanna G. M., Kallapur, Suhas G., Jobe, Alan H., Kramer, Boris W.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517680/
https://ncbi.nlm.nih.gov/pubmed/22962010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00280.2011
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