Insights from a novel model of slow-transit constipation generated by partial outlet obstruction in the murine large intestine

The mechanisms underlying slow-transit constipation (STC) are unclear. In 50% of patients with STC, some form of outlet obstruction has been reported; also an elongated colon has been linked to patients with STC. Our aims were 1) to develop a murine model of STC induced by partial outlet obstruction...

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Bibliografiske detaljer
Main Authors: Heredia, Dante J., Grainger, Nathan, McCann, Conor J., Smith, Terence K.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Neuroregulation and Motility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517665/
https://ncbi.nlm.nih.gov/pubmed/22961801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00238.2012
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