Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

BACKGROUND: We aimed to identify novel genetic variants affecting asthma risk, since these might provide novel insights into molecular mechanisms underlying asthma. METHODS: We performed a genome-wide association study (GWAS) in 2,669 physician-diagnosed asthmatics and 4,528 controls from Australia....

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Detalhes bibliográficos
Main Authors: Ferreira, Manuel A.R., Matheson, Melanie C., Duffy, David L., Marks, Guy B., Hui, Jennie, Le Souëf, Peter, Danoy, Patrick, Baltic, Svetlana, Nyholt, Dale R., Jenkins, Mark, Hayden, Catherine, Willemsen, Gonneke, Ang, Wei, Kuokkanen, Mikko, Beilby, John, Cheah, Faang, de Geus, Eco J. C., Ramasamy, Adaikalavan, Vedantam, Sailaja, Salomaa, Veikko, Madden, Pamela A., Heath, Andrew C., Hopper, John L., Visscher, Peter M., Musk, Bill, Leeder, Stephen R., Jarvelin, Marjo-Riitta, Pennell, Craig, Boomsma, Dorret I., Hirschhorn, Joel, Walters, Haydn, Martin, Nicholas G., James, Alan, Jones, Graham, Abramson, Michael J., Robertson, Colin F., Dharmage, Shyamali C., Brown, Matthew A., Montgomery, Grant W., Thompson, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517659/
https://ncbi.nlm.nih.gov/pubmed/21907864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(11)60874-X
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